基因表达图谱网站（GenePaint.org）：小鼠胚胎基因表达模式图谱。
GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
作者信息
Visel Axel, Thaller Christina, Eichele Gregor
机构信息
Max Planck Institute of Experimental Endocrinology, Feodor-Lynen-Strasse 7, D-30625 Hannover, Germany.
出版信息
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6. doi: 10.1093/nar/gkh029.
High-throughput instruments were recently developed to determine gene expression patterns on tissue sections by RNA in situ hybridization. The resulting images of gene expression patterns, chiefly of E14.5 mouse embryos, are accessible to the public at http://www.genepaint.org. This relational database is searchable for gene identifiers and RNA probe sequences. Moreover, patterns and intensity of expression in approximately 100 different embryonic tissues are annotated and can be searched using a standardized catalog of anatomical structures. A virtual microscope tool, the Zoom Image Server, was implemented in GenePaint.org and permits interactive zooming and panning across approximately 15,000 high-resolution images.
最近开发了高通量仪器，通过RNA原位杂交来确定组织切片上的基因表达模式。通过该技术获得的基因表达模式图像，主要是E14.5小鼠胚胎的图像，可在http://www.genepaint.org上供公众使用。这个关系型数据库可通过基因标识符和RNA探针序列进行搜索。此外，还对大约100种不同胚胎组织中的表达模式和强度进行了注释，并且可以使用标准化的解剖结构目录进行搜索。GenePaint.org中实现了一个虚拟显微镜工具——缩放图像服务器，它允许在大约15,000张高分辨率图像上进行交互式缩放和平移。
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