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糖类对盘基网柄菌发育的抑制作用。

Inhibition of development in Dictyostelium discoideum by sugars.

作者信息

Rickenberg H V, Rahmsdorf H J, Campbell A, North M J, Kwasniak J, Ashworth J M

出版信息

J Bacteriol. 1975 Oct;124(1):212-9. doi: 10.1128/jb.124.1.212-219.1975.

Abstract

Sugars such as glucose, maltose, and trehalose, which are metabolized by Dictyostelium discoideum and which enhance vegetative growth, inhibit the development of the slime mold at concentrations which stimulate growth maximally. They block the acquisition of aggregation competence as well as aggregation. The same sugars also inhibit the degradation of preformed glycogen ribonucleic acid, and protein, which is characteristic of development and which occurs when the amoebas are starved by incubation in dilute phosphate buffer.

摘要

诸如葡萄糖、麦芽糖和海藻糖等糖类,可被盘基网柄菌代谢并促进营养生长,但在能最大程度刺激生长的浓度下,却会抑制黏菌的发育。它们会阻碍聚集能力的获得以及聚集过程。同样的糖类还会抑制预先形成的糖原、核糖核酸和蛋白质的降解,而这种降解是发育的特征,且当变形虫在稀磷酸盐缓冲液中孵育而饥饿时就会发生。

相似文献

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Kinetic of 5-bromodeoxyuridine action on Dictyostelium discoideum growth and development.
Exp Cell Res. 1976 Mar 1;98(1):184-90. doi: 10.1016/0014-4827(76)90478-x.

本文引用的文献

3
ENVIRONMENTAL CONTROL OF THE COURSE OF DEVELOPMENT IN DICTYOSTELIUM DISCOIDEUM.
J Gen Microbiol. 1963 Aug;32:195-207. doi: 10.1099/00221287-32-2-195.
4
Estimation of glycogen in small amounts of tissue.少量组织中糖原的测定。
Anal Biochem. 1965 May;11(2):256-65. doi: 10.1016/0003-2697(65)90013-8.

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