Boelens R, Gualerzi C O
Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Curr Protein Pept Sci. 2002 Feb;3(1):107-19. doi: 10.2174/1389203023380765.
Bacteria require three initiation factors, IF1, IF2 and IF3, to start protein synthesis. In the last few years the elucidation of both structural and mechanistic aspects pertaining to these proteins has made substantial progress. In this article we outline the translation initiation process in bacteria and review these recent developments giving a summary of the main features of the structure and function of the initiation factors.
细菌需要三种起始因子，即IF1、IF2和IF3来启动蛋白质合成。在过去几年中，对这些蛋白质的结构和机制方面的阐释取得了重大进展。在本文中，我们概述了细菌中的翻译起始过程，并回顾了这些最新进展，总结了起始因子结构和功能的主要特征。
