Lian Jie, Goldstein Abraham, Donchin Emanuel, He Bin
Department of Bioengineering, University of Illinois at Chicago, USA.
Brain Topogr. 2002 Fall;15(1):29-36. doi: 10.1023/a:1019988422338.
Previous findings suggest that episodic memory encoding is subserved by different brain structures that interplay and transform experience into memories. The present study aims to identify topographic location of the underlying neural generators, and correlate their activities with the subsequent memory effect using electrophysiological neuroimaging of the event-related potentials (ERPs) recorded from 11 healthy subjects participating in word encoding tasks. Cortical potentials were imaged noninvasively from scalp ERPs. Different levels of brain activation were found in the left inferior prefrontal, left temporal and left parietal lobes with different latencies after onset of event. It is concluded that these regions work jointly across both spatial and temporal domains to promote verbal memory formation.
先前的研究结果表明，情景记忆编码由不同的脑结构支持，这些脑结构相互作用并将经历转化为记忆。本研究旨在确定潜在神经发生器的地形位置，并使用从11名参与单词编码任务的健康受试者记录的事件相关电位（ERP）的电生理神经成像，将它们的活动与随后的记忆效应相关联。通过头皮ERP对皮质电位进行无创成像。在事件开始后的不同潜伏期，左前额叶下部、左颞叶和左顶叶发现了不同程度的脑激活。得出的结论是，这些区域在空间和时间域共同发挥作用，以促进言语记忆的形成。
