Sillanpää Mikko J
Rolf Nevanlinna Institute, University of Helsinki, Finland.
Ann Med. 2002;34(4):291-8. doi: 10.1080/078538902320322556.
Genetic mapping in analysis of medical disease is performed under several assumptions and (experimental) conditions, which are made about the data in general and the disease in particular. Here we discuss these conditions, what they mean, and what kind of deleterious effects they might have on the analysis. We also illustrate how to proceed and what kind of possibilities the statistical analysis may provide to medical scientists.
医学疾病分析中的基因定位是在若干假设和(实验)条件下进行的,这些假设和条件是针对一般数据特别是疾病数据做出的。在此,我们将讨论这些条件、它们的含义以及它们可能对分析产生的有害影响。我们还将说明如何进行分析,以及统计分析可能为医学科学家提供哪些可能性。