Kindstrand E, Nilsson B Y, Hovmark A, Pirskanen R, Asbrink E
Karolinska Institute, Department of Neurology, Huddinge University Hospital, Stockholm, Sweden.
Acta Neurol Scand. 2002 Nov;106(5):253-7. doi: 10.1034/j.1600-0404.2002.01336.x.
Forty-seven patients with the late borrelial manifestation acrodermatitis chronica atrophicans (ACA) and with objective neurological and/or neurophysiological findings were followed up after antibiotic treatment with dermatological, serological, neurological and neurophysiological controls. Despite a good therapeutic effect on ACA lesions, specific antibody values and symptoms of irritative nerve lesions, the objective neurological and neurophysiological findings of nerve deficit remained unchanged. There was no progress of neuropathy findings during the follow-up time. Our interpretation of the results is that the remaining neuropathy signs after treatment of ACA are neurological sequelae and not manifestations of persisting Borrelia infection.
47例患有晚期莱姆病表现——慢性萎缩性肢端皮炎（ACA）且有客观神经学和/或神经生理学发现的患者，在接受抗生素治疗后，进行了皮肤科、血清学、神经学和神经生理学检查的随访。尽管抗生素治疗对ACA皮损、特异性抗体值及刺激性神经损伤症状有良好疗效，但神经功能缺损的客观神经学和神经生理学发现仍未改变。在随访期间，神经病变的检查结果没有进展。我们对结果的解释是，ACA治疗后残留的神经病变体征是神经后遗症，而非持续存在的伯氏疏螺旋体感染的表现。
