Hopf H C
J Neurol Neurosurg Psychiatry. 1975 May;38(5):452-8. doi: 10.1136/jnnp.38.5.452.
Acrodermatitis chronica atrophicans is a dermatological condition that takes a chronically progressive course and finally leads to a widespread atrophy of the skin. Involvement of the peripheral nervous system is frequently observed, predominantly a sensory polyneuropathy. General reactions, the effect of penicillin treatment, the histological findings, and reports concerning a communicable agent transmittable from human to human as well in tissue cultures point to an infectious disease. Acrodermatitis chronica atrophicans follows a peculiar geographical distribution forming clusters of high prevalence in certain regions. Transmission by ticks is suggested.
慢性萎缩性肢端皮炎是一种皮肤病，病程呈慢性进行性，最终导致皮肤广泛萎缩。常观察到外周神经系统受累，主要是感觉性多神经病。全身反应、青霉素治疗效果、组织学发现以及关于在人体和组织培养中均可人际传播的病原体的报告均指向一种传染病。慢性萎缩性肢端皮炎呈现出特殊的地理分布，在某些地区形成高发病集群。提示通过蜱传播。
