中心粒复制：中心蛋白是答案所在？

Centriole duplication: centrin in on answers?

作者信息

Rice Luke M, Agard David A

机构信息

Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA.

出版信息

Curr Biol. 2002 Sep 17;12(18):R618-9. doi: 10.1016/s0960-9822(02)01133-8.

DOI:10.1016/s0960-9822(02)01133-8

PMID:12372266

Abstract

Many aspects of centriole biology remain mysterious. A new study has shed light on the role of the centriolar protein centrin-2: reducing levels of centrin-2 in HeLa cells has been found to block centriole duplication, eventually leading to cell death.

摘要

中心粒生物学的许多方面仍然神秘莫测。一项新研究揭示了中心粒蛋白中心素-2的作用：研究发现，降低HeLa细胞中中心素-2的水平会阻止中心粒复制，最终导致细胞死亡。