Höllriegl Vera, Werner Eckhard, Roth Paul, Schramel Peter, Wendler Iris
Institute of Radiation Protection, GSF - National Research Center for Environment and Health, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
Radiat Environ Biophys. 2002 Sep;41(3):179-83. doi: 10.1007/s00411-002-0162-7. Epub 2002 Aug 2.
The radioactive isotopes of strontium, mainly (90)Sr, which are common fission products, may significantly contribute to the internal exposure of the population in case of their accidental release into the environment and transfer to the food chain. For (90)Sr, the internal radiation dose is significantly dependent on the fractional absorption of the ingested activity (f(1)-value). Human data on the absorption of dietary strontium and of soluble forms of the element give values ranging from about 0.15 to 0.45 (up to 1.0) for adults. The International Commission on Radiological Protection (ICRP) has adopted f(1)-values of 0.6 for children of less than 1 year of age, 0.4 for children between 1 and 15 years and 0.3 for adolescents above 15 years of age. This study was aimed at investigating how far these values correspond to the actual uptake of strontium from contaminated foodstuffs. A methodology is presented that has been developed for preparing foodstuffs intrinsically labelled with stable isotopes and that will be used in tracer kinetic investigations. The results show that cress and salad can be adequately labelled, i.e. a strontium concentration of 1.36+/-0.47 g per kg of cress (wet weight) and of 0.29+/-0.04 g per kg of salad (wet weight) may be obtained within 15 days and 24 days, respectively. For the biokinetic investigations on humans, applying stable isotopes of Sr as tracers, about 0.1-1 mg strontium is required per volunteer, i.e. a few grams of the edible parts of the labelled material are sufficient.
锶的放射性同位素，主要是（90）Sr，是常见的裂变产物，一旦意外释放到环境中并转移到食物链，可能会显著增加人群的内照射剂量。对于（90）Sr，内照射剂量很大程度上取决于摄入活度的吸收分数（f(1)值）。关于成年人饮食中锶及该元素可溶形式吸收情况的人体数据显示，该值范围约为0.15至0.45（最高可达1.0）。国际放射防护委员会（ICRP）采用的f(1)值为：1岁以下儿童为0.6，1至15岁儿童为0.4，15岁以上青少年为0.3。本研究旨在调查这些值与从受污染食品中实际摄取锶的情况相符程度。本文介绍了一种已开发出的用于制备用稳定同位素进行固有标记的食品的方法，该方法将用于示踪动力学研究。结果表明，水芹和生菜可以得到充分标记，即在15天和24天内，分别可获得每千克水芹（湿重）含锶1.36±0.47克和每千克生菜（湿重）含锶0.29±0.04克。对于人体的生物动力学研究，应用稳定同位素锶作为示踪剂，每位志愿者大约需要0.1 - 1毫克锶，即几克标记材料的可食用部分就足够了。
