Dilber Embiya, Erduran Erol, Kalyoncu Mukaddes, Aynaci Fatma Müjgan, Okten Ayşenur, Ahmetoğlu Ali
Department of Paediatrics, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Scand J Infect Dis. 2002;34(9):689-92. doi: 10.1080/00365540210147840.
A 9-y-old girl was admitted with fever, weakness and weight loss. She had pancytopenia in peripheral blood, hypocellularity and hemophagocytosis in bone marrow. Disseminated tuberculosis was diagnosed after a long delay, with involvement of the lungs, bone marrow, liver, spleen and central nervous system. Tuberculosis can be a cause of hemophagocytosis and should be taken into account in the differential diagnosis of fever of unknown origin associated with pancytopenia and hemophagocytosis.
一名9岁女孩因发热、乏力和体重减轻入院。她外周血全血细胞减少,骨髓细胞减少并出现噬血细胞现象。经过长时间延误后诊断为播散性结核病,累及肺、骨髓、肝、脾和中枢神经系统。结核病可能是噬血细胞现象的病因,在与全血细胞减少和噬血细胞现象相关的不明原因发热的鉴别诊断中应予以考虑。