Ors Marianne, Lindgren Magnus, Blennow Gösta, Rosén Ingmar
Division of Clinical Neurophysiology, Department of Clinical Neuroscience, Lund University, S-221 85 Lund, Sweden.
Eur J Paediatr Neurol. 2002;6(5):249-60. doi: 10.1053/ejpn.2002.0607.
Auditory event-related brain potentials evoked in response to tone stimuli and to speech stimuli were recorded in a group of parents of children with specific language-impairment and a group of parents of normally speaking children. The parents of the language-impaired children showed longer P3 latencies than the parental control group in the speech task requiring a phonological discrimination, but did not differ from the controls in the linguistically non-demanding tone discrimination task. The longer P3 latency was associated with a positive parental history of language delay. There were no group differences concerning the N1 component in any of the tasks. The findings indicate that parents of children with specific language impairment show signs of deficient late-stage perceptual higher order linguistic processing, whereas the earlier central sensory detection stage of the phonological information is no different from the controls. Our observations are particularly interesting with regard to a study of the children of these two parental groups, where the language-impaired children showed longer P3 latencies than controls in both a tone task and a speech task, whereas there were no differences between the children concerning the N1 component. We propose that deficient late-stage auditory higher order perceptual processing as indexed by the longer P3 latency to speech stimuli observed both in children with specific language-impairment and in their parents may represent a constitutional trait, contributing to the language acquisition difficulties in these children.
我们记录了一组特定语言障碍儿童的父母和一组正常儿童的父母在对音调刺激和言语刺激做出反应时诱发的听觉事件相关脑电位。在需要语音辨别的言语任务中，语言障碍儿童的父母比作为对照的父母组表现出更长的P3潜伏期，但在对语言要求不高的音调辨别任务中，他们与对照组没有差异。较长的P3潜伏期与父母有语言发育迟缓的阳性家族史有关。在任何任务中，两组关于N1成分均无差异。研究结果表明，特定语言障碍儿童的父母表现出后期感知高阶语言处理不足的迹象，而语音信息的早期中枢感觉检测阶段与对照组没有差异。对于对这两组父母的孩子进行的一项研究而言，我们的观察结果特别有趣，在该研究中，语言障碍儿童在音调任务和言语任务中均比对照组表现出更长的P3潜伏期，而两组儿童在N1成分方面没有差异。我们提出，特定语言障碍儿童及其父母中观察到的对言语刺激的P3潜伏期延长所表明的后期听觉高阶感知处理不足，可能代表一种体质特征，导致这些儿童在语言习得方面存在困难。
