Sztriha László, Nork Michael
Department of Paediatrics, Faculty of Medicine and Health Sciences, United Arab Emirates University, United Arab Emirates.
Eur J Paediatr Neurol. 2002;6(4):229-32. doi: 10.1053/ejpn.2002.0599.
A patient with bilateral symmetrical frontoparietal polymicrogyria is reported. Severe developmental delay, mental retardation, spastic tetraplegia, and seizures were the main clinical features. Magnetic resonance imaging revealed bilateral thick cortex with irregular gyri and festoon-like grey-white matter junction in the frontoparietal areas. Bilateral frontoparietal polymicrogyria might represent either a severe form of a spectrum of malformations involving the frontoparietal area or a further variety of the congenital bilateral symmetrical polymicrogyria syndromes in addition to bilateral frontal polymicrogyria, bilateral perisylvian syndrome, and bilateral parasagittal parieto-occipital polymicrogyria.
本文报道了一例双侧对称性额顶叶多小脑回畸形患者。严重发育迟缓、智力障碍、痉挛性四肢瘫和癫痫发作是主要临床特征。磁共振成像显示双侧额叶皮质增厚,脑回不规则,额顶叶区域有花彩状灰白质交界。双侧额顶叶多小脑回畸形可能代表累及额顶叶区域的一系列畸形的严重形式,或者是除双侧额叶多小脑回畸形、双侧外侧裂周综合征和双侧矢状旁顶枕叶多小脑回畸形之外的先天性双侧对称性多小脑回畸形综合征的另一种类型。