腹腔镜胆囊切除术期间老年人QT间期及QT离散度增加：一项初步研究。
QT interval and QT dispersion increase in the elderly during laparoscopic cholecystectomy: a preliminary study.
作者信息
Egawa Hirotoshi, Minami Junichi, Fujii Kouichi, Hamaguchi Shinsuke, Okuda Yasuhisa, Kitajima Toshimitsu
机构信息
Department of Anesthesiology, Dokkyo University School of Medicine, Mibu, Tochigi, Japan.
出版信息
Can J Anaesth. 2002 Oct;49(8):805-9. doi: 10.1007/BF03017412.
PURPOSE
To compare the influence of a longer duration of intraperitoneal CO2 insufflation with head-up tilt on electrocardiogram indices during laparoscopic cholecystectomy between elderly and younger patients.
METHODS
Twelve elderly and 12 younger patients were studied. In all patients, intraperitoneal CO2 insufflation was performed for more than 150 min in the head-up position. RR interval, QT interval, the rate-corrected QT (QTc) interval, QT dispersion (QTD) and the rate-corrected QTD (QTcD) were measured.
RESULTS
The QT interval and the QTc interval increased significantly from 120 to 150 min after CO2 insufflation in the elderly. The QTD and QTcD increased significantly during CO2 insufflation in both groups. Those were significantly greater in the elderly than in younger patients from 120 to 150 min after CO2 insufflation.
CONCLUSION
Longer duration of CO2 insufflation with head-up tilt is associated with a prolongation of the QT interval and the QTD in elderly patients. The clinical significance of these findings remains to be determined.
目的
比较老年患者和年轻患者在腹腔镜胆囊切除术期间，较长时间的头高位腹膜内二氧化碳气腹对心电图指标的影响。
方法
研究了12例老年患者和12例年轻患者。所有患者均在头高位进行了超过150分钟的腹膜内二氧化碳气腹。测量RR间期、QT间期、校正心率后的QT（QTc）间期、QT离散度（QTD）和校正心率后的QTD（QTcD）。
结果
老年患者在二氧化碳气腹后120至150分钟时，QT间期和QTc间期显著增加。两组在二氧化碳气腹期间QTD和QTcD均显著增加。在二氧化碳气腹后120至150分钟时，老年患者的这些指标显著高于年轻患者。
结论
头高位较长时间的二氧化碳气腹与老年患者QT间期延长和QTD增加有关。这些发现的临床意义尚待确定。
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