Haytaç M Cenk, Oztunç Haluk, Mete Ufuk O, Kaya Mehmet
Department of Periodontology, Cukurova University, Bacali, Adana, Turkey.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 Oct;94(4):479-84. doi: 10.1067/moe.2002.127584.
Rothmund-Thomson syndrome (RTS) is an extremely rare genetic disorder characterized by poikilodermatous skin changes, photosensitivity, and an increased risk of developing skin and bone malignancies. In this case report, the dental and periodontal features of RTS in a 16-year-old female patient are presented. The transmission electron microscopy performed on a gingival biopsy specimen showed structural defects of connective tissue. If the unusual ultrastructural findings of this case are confirmed as being consistent with other RTS patients, it is our opinion that this syndrome can be considered among the systemic diseases associated with early-onset periodontitis.
罗思蒙德-汤姆森综合征（RTS）是一种极为罕见的遗传性疾病，其特征为皮肤异色症样皮肤改变、光敏性以及发生皮肤和骨恶性肿瘤的风险增加。在本病例报告中，呈现了一名16岁女性RTS患者的牙齿和牙周特征。对牙龈活检标本进行的透射电子显微镜检查显示结缔组织存在结构缺陷。如果本病例不同寻常的超微结构发现被证实与其他RTS患者一致，我们认为该综合征可被视为与早发性牙周炎相关的全身性疾病之一。
