Lang A G, Peterson H A
J Trauma. 1976 Dec;16(12):993-9. doi: 10.1097/00005373-197612000-00010.
Review of the laboratory and clinical findings and treatment of eight patients with osteomyelitis of the foot after puncture wounds revealed that: 1) osteomyelitis after puncture wounds is a infrequent but potentially serious complication, with significant morbidity; 2) osteomyelitis is frequently preceded by inadequate primary care for simple puncture wounds, and when treatment is appropriate, osteomyelitis usually can be avoided; 3) P. aeruginosa is the most commonly recovered organism; 4) the clinical presentation is characterized by a lack of systemic toxicity, paucity of laboratory abnormalities, and evidence of a localized infection process and the patient may be asymptomatic for a few days to several months after the injury before presentation of the osteomyelitis; and 5) once the infection has become established, treatment must be aggressive, including surgical debridement.
对8例足部刺伤后骨髓炎患者的实验室检查、临床发现及治疗情况进行回顾后发现：1）刺伤后骨髓炎是一种罕见但可能严重的并发症，具有较高的发病率；2）骨髓炎常因对简单刺伤的初期处理不当所致，若治疗得当，通常可避免骨髓炎的发生；3）铜绿假单胞菌是最常分离出的病原体；4）临床表现为缺乏全身中毒症状、实验室异常表现较少、有局部感染过程的证据，且患者在骨髓炎出现前，受伤后数天至数月可能无症状；5）一旦感染确立，治疗必须积极，包括手术清创。
