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血栓性血小板减少性紫癜的血浆置换:2例报告

Plasma exchange for thrombotic thrombocytopenic purpura: report of 2 cases.

作者信息

Yin Fang, Meng Fan-Yi, Zhou Shu-Yun, Niu Jing-Na, Li Jun-Ti, Liu Fu

机构信息

Department of Hematology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.

出版信息

Di Yi Jun Yi Da Xue Xue Bao. 2002 Aug;22(8):750-1.

PMID:12376271
Abstract

Two patients with thrombotic thrombocytopenic purpura (TTP) were treated with daily plasma exchange with fresh frozen plasma of the plasma volume of the body (40 mg/kg . b.w.), in combination with red blood cell transfusion. The clinical symptoms resolved immediately and the parameters of laboratory examination improved promptly after the treatment, and follow-up of the 2 patients revealed no recurrent TTP episodes. This result indicates that plasma exchange is obviously superior to traditional treatment modalities and has significantly changed the course of TTP.

摘要

两名血栓性血小板减少性紫癜(TTP)患者接受了每日一次的血浆置换治疗,置换量为全身血浆量(40mg/kg体重)的新鲜冰冻血浆,并联合红细胞输注。治疗后临床症状立即缓解,实验室检查参数迅速改善,对这两名患者的随访显示未出现TTP复发。这一结果表明血浆置换明显优于传统治疗方式,并显著改变了TTP的病程。

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