Guss Janet L, Kissileff Harry R, Devlin Michael J, Zimmerli Ellen, Walsh B Timothy
Obesity Research Center, St. Luke's/Roosevelt Hospital, New York, New York 10025, USA.
Obes Res. 2002 Oct;10(10):1021-9. doi: 10.1038/oby.2002.139.
To determine whether meal size is related to body mass index (BMI) in obese subjects with binge-eating disorder (BED).
Five groups of subjects each consumed two laboratory-test meals on nonconsecutive days. Forty-two women, categorized by BMI and BED diagnosis, were instructed to "binge" during one meal and to eat "normally" during another. Eighteen women had BMI values >38 kg/m(2) (more-obese) and 17 had BMI values between 28 to 32 kg/m(2) (less-obese). Twelve of the more-obese and nine of the less-obese individuals met Diagnostic and Statistical Manual (DSM)-IV criteria for BED. Seven normal-weight women also participated as controls.
Subjects with BED ate significantly more in both meals than subjects without BED. Binge meals were significantly larger than normal meals only among subjects with BED. The more-obese subjects with BED ate significantly more than the less-obese subjects with BED, but only when they were asked to binge. Intake of the binge meal was significantly, positively correlated with BMI among subjects with BED. Subjects with BED reported significantly higher satiety ratings after the binge than after the normal meal, but subjects without BED reported similar ratings after both meals. Regardless of instructions and diagnosis, obese subjects consumed a significantly higher percentage of energy from fat (38.5%) than did normal-weight subjects (30.8%).
During binge meals, the energy intake of subjects with BED is greater than that of individuals of similar body weight without BED and is positively correlated with BMI.
确定暴饮暴食症（BED）肥胖受试者的进餐量是否与体重指数（BMI）相关。
五组受试者在非连续日期各食用两顿实验室测试餐。根据BMI和BED诊断进行分类的42名女性，被要求在一顿餐时“暴饮暴食”，在另一顿餐时“正常进食”。18名女性的BMI值>38 kg/m²（更肥胖），17名女性的BMI值在28至32 kg/m²之间（较不肥胖）。12名更肥胖者和9名较不肥胖者符合《精神疾病诊断与统计手册》（DSM）-IV中BED的标准。7名体重正常的女性也作为对照参与研究。
患有BED的受试者在两餐中的进食量均显著多于未患BED的受试者。只有在患有BED的受试者中，暴饮暴食餐明显大于正常餐。患有BED的更肥胖受试者比患有BED的较不肥胖受试者进食量显著更多，但仅在被要求暴饮暴食时如此。在患有BED的受试者中，暴饮暴食餐的摄入量与BMI显著正相关。患有BED的受试者在暴饮暴食后报告的饱腹感评分显著高于正常餐后，但未患BED的受试者在两餐后报告的评分相似。无论指示和诊断如何，肥胖受试者从脂肪中摄入的能量百分比（38.5%）显著高于体重正常的受试者（30.8%）。
在暴饮暴食餐期间，患有BED的受试者的能量摄入量大于体重相似但未患BED的个体，且与BMI呈正相关。
