Werner M, Delling G
Abteilung Osteopathologie, Pathologisches Institut, Universitätsklinikum Hamburg-Eppendorf, Germany.
Pathologe. 2002 Sep;23(5):340-50. doi: 10.1007/s00292-002-0567-8. Epub 2002 Aug 27.
Giant cell-rich bone lesions consist of tumor-like lesions and true neoplastic giant cell tumors. In this study it was investigated whether DNA cytometry may contribute to the differential diagnosis between aneurysmal bone cysts and giant cell tumors. Statistically significant differences in the frequency of tetraploid stemlines were detected. Nevertheless, the knowledge of age, localization and radiological signs in addition to morphological findings are essential to distinguish between these lesions.
富含巨细胞的骨病变包括肿瘤样病变和真正的肿瘤性巨细胞瘤。在本研究中，调查了DNA细胞计数法是否有助于骨动脉瘤样囊肿和巨细胞瘤之间的鉴别诊断。检测到四倍体干系频率存在统计学显著差异。然而，除形态学表现外，了解年龄、部位和放射学征象对于区分这些病变至关重要。
