Freudenmann R W
Universitätsklinik Ulm Abteilung Psychiatrie III, Ulm, Germany.
Fortschr Neurol Psychiatr. 2002 Oct;70(10):531-41. doi: 10.1055/s-2002-34666.
This paper gives an up-to-date review on delusional parasitosis (DP) and particularly meets clinical interests. Facing the lack of clear guidelines for clinical practice an efficient diagnostic staircase procedure is presented. The different approaches in the therapy of DP are reviewed and summed up in a checklist. The available information on the therapeutic gold standard, the neuroleptic agent pimozide, is discussed. Symptoms and clinical characteristics of DP are presented partly based on material from an internet website run by patients. Moreover, this paper delivers a comprehensive literature review on the pathogenesis of DP and its classification. To conclude, possible future therapies in DP, e. g. serotonin-dopamine-antagonists, as well as current methods in research on hallucinations are discussed.
本文对妄想性寄生虫病(DP)进行了最新综述,尤其符合临床需求。鉴于临床实践缺乏明确指南,本文提出了一种有效的诊断阶梯程序。对DP治疗的不同方法进行了综述,并归纳在一份清单中。讨论了关于治疗金标准——抗精神病药物匹莫齐特的现有信息。DP的症状和临床特征部分基于患者运营的一个互联网网站提供的资料。此外,本文还对DP的发病机制及其分类进行了全面的文献综述。最后,讨论了DP未来可能的治疗方法,如5-羟色胺-多巴胺拮抗剂,以及当前幻觉研究方法。