Beric A, Kelly P J, Rezai A, Sterio D, Mogilner A, Zonenshayn M, Kopell B
Department of Neurosurgery, NYU School of Medicine, New York 10003, USA.
Stereotact Funct Neurosurg. 2001;77(1-4):73-8. doi: 10.1159/000064600.
Although technological advances have reduced device-related complications, DBS surgery still carries a significant risk of transient and permanent complications. We report our experience in 86 patients and 149 DBS implants. Patients with Parkinson's disease, essential tremor and dystonia were treated. There were 8 perioperative, 8 postoperative, 9 hardware-related complications and 4 stimulation-induced side effects. Only 5 patients (6%) sustained some persistent neurological sequelae, however, 26 of the 86 patients undergoing 149 DBS implants in this series experienced some untoward event with the procedure. Although there were no fatalities or permanent severe disabilities encountered, it is important to extend the informed consent to include all potential complications.
尽管技术进步已减少了与设备相关的并发症,但脑深部电刺激(DBS)手术仍存在显著的短暂性和永久性并发症风险。我们报告了86例患者和149次DBS植入手术的经验。治疗了帕金森病、特发性震颤和肌张力障碍患者。有8例围手术期并发症、8例术后并发症、9例与硬件相关的并发症以及4例刺激引起的副作用。只有5例患者(6%)出现了一些持续性神经后遗症,然而,在本系列中接受149次DBS植入手术的86例患者中有26例在手术过程中经历了一些不良事件。尽管未遇到死亡或永久性严重残疾情况,但扩大知情同意范围以涵盖所有潜在并发症很重要。