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内侧颞叶区域的显微解剖与颞下杏仁海马切除术

Microanatomy of medial temporal area and subtemporal amygdalohippocampectomy.

作者信息

Hori T, Yamane F, Takenobu A

机构信息

Department of Neurosurgery, Tokyo Women's Medical University, Japan.

出版信息

Stereotact Funct Neurosurg. 2001;77(1-4):208-12. doi: 10.1159/000064594.

Abstract

For seizure control in temporal lobe epilepsy, the head of the hippocampus to the choroidal point, parahippocampal gyrus, entorhinal area, uncus, and at least the basolateral nucleus of the amygdala should be completely removed. The subtemporal approach should be selected for removal of these structures, and it does not interrupt the temporal stem and optic radiation. Pre- and postoperative neuropsychological examinations revealed that there is no significant decline of scores of various examinations including WAIS, WMS, Randt memory, and verbal associates learning tests, even if the resection were performed on the language dominant side. Seizure control for the 20 non-lesional patients operated with this approach is 60% (Class I and II), without definite permanent complications.

摘要

对于颞叶癫痫的癫痫控制,应完全切除海马头部至脉络丛点、海马旁回、内嗅区、钩回以及至少杏仁核的基底外侧核。应选择颞下入路切除这些结构,且该入路不会中断颞叶干和视辐射。术前和术后的神经心理学检查显示,即使在语言优势侧进行切除,包括韦氏成人智力量表(WAIS)、韦氏记忆量表(WMS)、兰氏记忆测验(Randt memory)和言语联想学习测试等各项检查的分数也没有显著下降。采用该方法手术的20例非病变患者的癫痫控制率为60%(I级和II级),且无明确的永久性并发症。

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