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脑室炎后自愈性脑积水——临床经验与实验思考(作者译)

[Self-cured hydrocephalus following ventriculitis--clinical experience and experimental consideration (author's transl)].

作者信息

Mori K, Murata T, Handa H

出版信息

No Shinkei Geka. 1975 Jul;3(7):599-605.

PMID:1237812
Abstract

Dynamics of CSF circulation is often altered in the presence of intracranial pathology especially in hydrocephalus. Most neurosurgeons acknowledge that the status of hydrocephalus often changes regardless of the type of treatment. In the follow-up of hydrocephalic children who under-went shunting operation, not a few hydrocephalic children have been doing well in spite of shunt malfunction for a long period. Interestingly enough, we have experienced the children who need no longer shunt after shunt infection complicated by ventriculitis. These cases differ from so-called spontaneously "arrested hydrocephalus", in that the latter develops in not severe hydrocephalus during the course of natural history or after shunt not complicated by serious infection. Consequently, we define these cases "self-cured hydrocephalus" following ventriculitis. Recently we experienced a similar case as mentioned above at the Kyoto University Hospital. We reported the case and made some inquiry into pathogenesis of "self-cured hydrocephalus". We hope that further inventigation of the similar cases along with experimental studies might give us a key to establish a radical treatment for hydrocephalus.

摘要

脑脊液循环动力学在颅内病变尤其是脑积水存在时常常发生改变。大多数神经外科医生承认,无论治疗类型如何,脑积水的状态常常会发生变化。在接受分流手术的脑积水患儿的随访中,不少脑积水患儿尽管长期存在分流故障,但情况一直良好。有趣的是,我们遇到过一些患儿,在分流感染并发脑室炎后不再需要分流。这些病例与所谓的自发“静止性脑积水”不同,后者发生在自然病程中不太严重的脑积水或分流后未并发严重感染的情况下。因此,我们将这些病例定义为脑室炎后的“自愈性脑积水”。最近,我们在京都大学医院遇到了上述类似病例。我们报告了该病例,并对“自愈性脑积水”的发病机制进行了一些探究。我们希望对类似病例的进一步研究以及实验研究能够为我们提供建立脑积水根治性治疗方法的关键。

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