Mann D R, Korowitz C D, Barraclough C A
Proc Soc Exp Biol Med. 1975 Oct;150(1):115-20. doi: 10.3181/00379727-150-38985.
In this study we have demonstrated that acute adrenalectomy (1000 hr proestrus) has no effect on the release of LH on proestrous afternoon. However, chronic adrenalectomy results in the loss of some factor responsible for synchronizing the preovulatory LH surge. Since this investigator has shown previously (15) that progesterone can influence the timing of LH release in ovariectomized and ovariectomized-adrenalectomized animals, it is most likely that adrenal progesterone is involved in synchronizing this event.
在本研究中,我们已经证明,急性肾上腺切除术(发情前期1000小时)对发情前期下午促黄体生成素(LH)的释放没有影响。然而,慢性肾上腺切除术会导致负责同步排卵前LH峰的某些因子丧失。由于该研究者之前已经表明(15),孕酮可以影响去卵巢和去卵巢-肾上腺切除动物中LH释放的时间,因此很可能肾上腺孕酮参与了这一事件的同步。