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鼻中隔纤维切断对大鼠旷场社交行为的影响。

Effects of septal-fiber knife cuts on rat open-field social behavior.

作者信息

Poplawsky A

出版信息

Physiol Behav. 1975 Aug;15(2):177-84. doi: 10.1016/0031-9384(75)90233-4.

DOI:10.1016/0031-9384(75)90233-4
PMID:1237907
Abstract

Rats that received various septal fiber knife cuts were observed in an open-field to assess preoperative and postoperative social behaviors. Ventral septal fiber knife cuts isolated septum knife cuts and anterior-lateral knife cuts result in increases in contact time; in decreasesin aggressive behaviors/100 sec contact time; and in no change in the number of contacts. Anterior, posterior, or dorsal fiber knife cuts failed to produce significant changes in contact time, aggressive or submissive behavior, number of contacts, and activity. A postoperative decrease in initiating aggressive behaviors may explain increases in contact time following ventral septal fiber, isolated septum, and anterior-lateral knife cuts. The ventral-septal fiber tracts were critical in mediating social behavior, imply that - in relation to social behavior - there is a functional connection through the ventral fibers between structures beneath the septum (hypothalamus) and the septal nuclei.

摘要

对接受各种隔区纤维切断术的大鼠在旷场中进行观察,以评估术前和术后的社会行为。腹侧隔区纤维切断术、孤立隔区切断术和前外侧切断术导致接触时间增加;攻击性行为/100秒接触时间减少;接触次数无变化。前、后或背侧纤维切断术未能使接触时间、攻击或顺从行为、接触次数和活动产生显著变化。术后攻击性行为发起的减少可能解释了腹侧隔区纤维、孤立隔区和前外侧切断术后接触时间的增加。腹侧隔区纤维束在介导社会行为中起关键作用,这意味着——就社会行为而言——在隔区下方的结构(下丘脑)和隔核之间通过腹侧纤维存在功能联系。

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