Carucci John A
Department of Dermatology, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA.
Dermatol Clin. 2002 Oct;20(4):701-8. doi: 10.1016/s0733-8635(02)00032-3.
Surgical excision with clear margins remains the treatment of choice for melanoma. Under appropriate conditions MMS may offer a means of achieving clear margins while sparing normal tissue. This requires a Mohs' surgeon expert in interpretation of melanocytic lesions and excellent technical support. As the popularity of special histologic stains continues to grow these may offer and additional means to increase sensitivity and specificity in the detection of melanoma.
手术切除切缘阴性仍然是黑色素瘤的首选治疗方法。在适当条件下,莫氏显微外科手术(MMS)可能提供一种在保留正常组织的同时实现切缘阴性的方法。这需要一位擅长解读黑素细胞性病变的莫氏外科医生以及出色的技术支持。随着特殊组织学染色方法的日益普及,这些方法可能提供提高黑色素瘤检测敏感性和特异性的额外手段。