Department of Dermatology, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Dermatol Clin. 2012 Jul;30(3):503-15. doi: 10.1016/j.det.2012.04.010. Epub 2012 Jun 5.
For melanoma treatment, the primary goal is complete removal with histologically negative margins. Mohs micrographic surgery (MMS) has been extensively used and studied for the treatment of nonmelanoma skin cancer, particularly at sites where tissue conservation is vital. The use of MMS for melanoma treatment has yet to become widely accepted owing to difficulties in histologic interpretation, among other factors. MMS may offer lower recurrence rates and improved survival when compared with historical controls for standard excision. Continued advances in MMS technique and immunohistochemical staining have allowed the technique to gain further support.
对于黑素瘤的治疗，主要目标是完全切除且组织学切缘阴性。Mohs 显微外科手术（MMS）已广泛用于治疗非黑素瘤皮肤癌，特别是在组织保存至关重要的部位。由于组织学解释等因素，MMS 治疗黑素瘤尚未被广泛接受。与标准切除的历史对照相比，MMS 可能具有更低的复发率和更好的生存率。MMS 技术和免疫组织化学染色的不断进步使其得到了进一步的支持。
