Rabinovich C Egla
Division of Pediatric Rheumatology, Department of Pediatrics, Duke University Medical Center, Box 3212, Durham, NC 27710, USA.
Rheum Dis Clin North Am. 2002 Aug;28(3):655-67, vii-viii. doi: 10.1016/s0889-857x(02)00017-0.
There is an increasing appreciation among physicians about the importance of bone health in children as a potential modifiable risk factor for development of osteoporosis later in life. Many unanswered questions about normal pediatric bone health make the treatment and clinical investigation of bone disease in children with chronic rheumatic diseases challenging. Understanding normal bone biology along with the epidemiology and diagnosis of osteoporosis is the key to the understanding of the potential for abnormal bone metabolism in the juvenile rheumatic diseases.
医生们越来越认识到儿童骨骼健康的重要性,它是日后发生骨质疏松症的一个潜在可改变风险因素。关于正常儿童骨骼健康仍有许多未解答的问题,这使得对患有慢性风湿性疾病儿童的骨病治疗和临床研究颇具挑战性。了解正常骨生物学以及骨质疏松症的流行病学和诊断方法,是理解青少年风湿性疾病中骨代谢异常可能性的关键。