Pharmacological approaches to defining the role of chaperones in aging and prostate cancer progression.
作者信息
Harvey Sarah A, Jensen Keith O, Elmore Lynne W, Holt Shawn E
机构信息
Department of Pharmacology and Toxicology, Medical College of Virginia at Virginia Commonwealth University, Richmond 23298-0662, USA.
出版信息
Cell Stress Chaperones. 2002 Apr;7(2):230-4. doi: 10.1379/1466-1268(2002)007<0230:patdtr>2.0.co;2.
Abstract
摘要
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本文引用的文献
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The serial cultivation of human diploid cell strains.人二倍体细胞株的连续培养。
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Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease.伴侣蛋白对帕金森病果蝇模型中α-突触核蛋白毒性的抑制作用。
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The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability.最短的端粒而非平均端粒长度，对细胞活力和染色体稳定性至关重要。
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A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression.前列腺癌进展过程中伴侣蛋白介导的端粒酶调控的一种新机制。
Cancer Res. 2001 Jun 15;61(12):4791-6.
5
Stable association of hsp90 and p23, but Not hsp70, with active human telomerase.热休克蛋白90（hsp90）和p23而非热休克蛋白70（hsp70）与活性人端粒酶的稳定结合。
J Biol Chem. 2001 May 11;276(19):15571-4. doi: 10.1074/jbc.C100055200. Epub 2001 Mar 23.
6
The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone.热休克蛋白90拮抗剂新生霉素与伴侣蛋白羧基末端一个先前未被识别的ATP结合结构域相互作用。
J Biol Chem. 2000 Nov 24;275(47):37181-6. doi: 10.1074/jbc.M003701200.
7
Synthesis and evaluation of geldanamycin-testosterone hybrids.格尔德霉素-睾酮杂合物的合成与评价
Bioorg Med Chem Lett. 2000 Jun 5;10(11):1303-6. doi: 10.1016/s0960-894x(00)00208-0.
8
Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases.一种诱导HER家族酪氨酸激酶选择性降解的格尔德霉素二聚体的鉴定。
Cancer Res. 2000 Apr 15;60(8):2090-4.
9
Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.单链断裂的积累是人类成纤维细胞中端粒缩短的主要原因。
Free Radic Biol Med. 2000 Jan 1;28(1):64-74. doi: 10.1016/s0891-5849(99)00207-5.
10
Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins.新生霉素及相关香豆素与热休克蛋白90依赖性信号蛋白的耗竭
J Natl Cancer Inst. 2000 Feb 2;92(3):242-8. doi: 10.1093/jnci/92.3.242.
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