Baliutaviciene D, Petrenko V, Zalinkevicius R
Department of Obstetrics and Gynecology, Kaunas University of Medicine, Kaunas, Lithuania.
Int J Gynaecol Obstet. 2002 Sep;78(3):207-11. doi: 10.1016/s0020-7292(02)00149-2.
To estimate the effect of selective diagnostic testing for gestational diabetes mellitus (GDM): (1) based on evaluation of risk factors; and (2) based on the recommendations of The Fourth Workshop-Conference on GDM.
A retrospective study was performed of 147 pregnancies complicated by GDM delivered in Kaunas University of Medicine Hospital. The maternal and fetal outcomes and the main risk factors were compared with the same data of a randomly selected 300 women with normal glucose tolerance testing. Logistic regression was used to estimate the odds ratios with 95% confidence interval (CI).
The prevalence of all risk factors was significantly higher in the group with GDM, but 29 of these women (23.13%) had no risk factors. Sixteen women (10.9%) with GDM were at low risk and would remain undiagnosed if selective screening would be used.
The recommendations not to test low-risk group women are doubtful and require further examination whereas universal screening of all pregnant women would be justified.
评估妊娠期糖尿病（GDM）选择性诊断检测的效果：（1）基于风险因素评估；（2）基于GDM第四次研讨会会议的建议。
对在考纳斯医科大学医院分娩的147例并发GDM的妊娠进行回顾性研究。将母婴结局和主要风险因素与随机选择的300例糖耐量试验正常女性的相同数据进行比较。采用逻辑回归估计比值比及95%置信区间（CI）。
GDM组所有风险因素的患病率均显著更高，但其中29名女性（23.13%）无风险因素。16名GDM女性（10.9%）属于低风险，如果采用选择性筛查将仍未被诊断。
不检测低风险组女性的建议值得怀疑，需要进一步研究，而对所有孕妇进行普遍筛查是合理的。
