Manuel D G, Schultz S E, Kopec J A
Institute for Clinical Evaluative Sciences, Toronto, Canada.
J Epidemiol Community Health. 2002 Nov;56(11):843-50. doi: 10.1136/jech.56.11.843.
To estimate the burden of illness from chronic disease and injury using a population based health survey, which contains both measures of chronic disease and a utility based health related quality of life (HRQOL) measure.
An adapted Sullivan method was used to calculate cause deleted health adjusted life expectancies for chronic conditions.
Ontario, Canada, 1996/97.
The 1996/97 Ontario Health Survey (n=35 527) was used to estimate the prevalence of chronic conditions. A cause deleted approach was used to estimate the impact of these conditions on the Health Utilities Index (HUI). Cause deleted probabilities of dying were derived with the cause eliminated life table technique and death data from vital statistics for Ontario 1996/97 (n=156 610).
Eliminating cardiovascular disease and cancer will cause an "expansion of morbidity", while eliminating mental conditions and musculosketal disorders will result in a "contraction of morbidity". The HUI score varies depending on chronic condition, age, and sex-most of which were assumed not to vary in previous summary measures of population health.
Health adjusted life expectancy estimated for chronic conditions using a utility based measure of health related quality of life from population health surveys addresses several limitations of previous studies that estimate the burden of disease using either a categorical measure of disability or expert opinion and related epidemiological evidence.
利用一项基于人群的健康调查评估慢性病和损伤的疾病负担,该调查包含慢性病测量指标以及基于效用的健康相关生活质量(HRQOL)测量指标。
采用一种改良的沙利文方法计算慢性病的病因去除健康调整预期寿命。
1996/97年,加拿大安大略省。
1996/97年安大略省健康调查(n = 35527)用于估计慢性病的患病率。采用病因去除法评估这些疾病对健康效用指数(HUI)的影响。通过病因去除生命表技术和1996/97年安大略省生命统计数据(n = 156610)得出病因去除死亡概率。
去除心血管疾病和癌症会导致“发病期延长”,而去除精神疾病和肌肉骨骼疾病会导致“发病期缩短”。HUI得分因慢性病、年龄和性别而异,而在以往人群健康综合测量中,大部分因素被假定为不变。
利用基于人群健康调查的健康相关生活质量效用测量指标估算慢性病的健康调整预期寿命,解决了以往研究的若干局限性,以往研究使用残疾分类测量指标或专家意见及相关流行病学证据来估算疾病负担。