An Kai-Nan
Division of Orthopedic Research, Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA.
Clin Orthop Relat Res. 2002 Oct(403 Suppl):S37-42. doi: 10.1097/00003086-200210001-00005.
The study of loading in the muscle is essential to better understanding the adaptation and plasticity of the muscle under pathologic or surgically-altered conditions. Muscle recruitment and muscle force are determined by the muscle's mechanical function as a joint mover and a joint stabilizer. The coordination of muscle contraction affects joint stability. However, the conditions of the joint passive constraints influence the muscle recruitment. Furthermore, muscle force is regulated based on muscle size, such as the physiologic cross-sectional area, and its physiology, namely, the length-tension and the tension-velocity relationship. Alterations of these physiologic relationships also will influence the overall mechanical function of the muscle.
研究肌肉负荷对于更好地理解病理或手术改变条件下肌肉的适应性和可塑性至关重要。肌肉募集和肌肉力量取决于肌肉作为关节运动器和关节稳定器的机械功能。肌肉收缩的协调性影响关节稳定性。然而，关节被动约束的条件会影响肌肉募集。此外，肌肉力量是根据肌肉大小（如生理横截面积）及其生理学特性（即长度-张力和张力-速度关系）来调节的。这些生理关系的改变也会影响肌肉的整体机械功能。
