Chang J W, Choi J Y, Lee B W, Kang U J, Chung S S
Department of Neurosurgery and Medical Research Centre, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Korea.
J Neurol Neurosurg Psychiatry. 2002 Nov;73(5):588-90. doi: 10.1136/jnnp.73.5.588.
Treatment with unilateral left globus pallidus internus (GPi) deep brain stimulation is reported in a patient with severe delayed onset post-traumatic cervical dystonia. He had sustained severe head trauma at the age of 17 and had developed a mild right hemiparesis. Three years after the head injury, cervical dystonia with head turning to the left side developed. Magnetic resonance imaging (MRI) showed a discrete GPi lesion on the left side. At the age of 23, he underwent unilateral left GPi deep brain stimulation. He experienced immediate but short lasting benefit from the microlesioning effect of the electrode. With activation of deep brain stimulation, there was significant improvement of the cervical dystonia, persisting for 12 months of follow up. This case underlines the importance of the globus pallidus internus in the generation and amelioration of cervical dystonia.
据报道，一名患有严重迟发性创伤后颈部肌张力障碍的患者接受了左侧苍白球内侧部（GPi）深部脑刺激治疗。他在17岁时遭受了严重的头部创伤，导致轻度右侧偏瘫。头部受伤三年后，出现了头部向左转动的颈部肌张力障碍。磁共振成像（MRI）显示左侧有一个离散的GPi病变。23岁时，他接受了左侧GPi深部脑刺激治疗。他从电极的微损伤效应中立即获得了短暂的益处。随着深部脑刺激的激活，颈部肌张力障碍有了显著改善，在12个月的随访中持续存在。该病例强调了苍白球内侧部在颈部肌张力障碍的发生和改善中的重要性。
