Kiese-Himmel C, Reeh M, Liebeck H, Zwirner P
Abteilung Phoniatrie und Pädaudiologie der Georg-August-Universität Göttingen, Germany.
Laryngorhinootologie. 2002 Oct;81(10):683-9. doi: 10.1055/s-2002-34999.
A pre-/posttherapeutic comparative study was carried out to investigate possible associations of voice symptoms, selected psychological factors and their changing.
A total of 11 patients with spasmodic dysphonia (adductor-type) subjected to botulinum-toxin-therapy. Patients had received treatment without any complications for at least 2 years. During that period of time, they received a minimum of 3 and a maximum of 9 injections (mean: 6).
Psychosocial data were measured before and after treatment using standardized psychological methods. The time span between measurements ranged from 1;8 to 4;6 years, with an average of 2;1 years.
On average, no somatic disorder, no clinically meaningful states of anxiety or pathological manifestations of personality traits could be detected, neither pre- nor posttherapeutically. The average stress load caused by life-changing-events was unobtrusive. Before treatment, 5 of 11 patients had an affective disorder in terms of a depressed mood. This caused a higher than average mean depressivity score for the group as a whole. It was no longer found posttherapeutically.
The depression is interpreted as a psychic reaction. An association between spasmodic voice symptoms and psychosocial genesis could not be proved.
开展一项治疗前/后对比研究，以调查嗓音症状、选定的心理因素及其变化之间可能存在的关联。
总共11例痉挛性发声障碍（内收型）患者接受了肉毒杆菌毒素治疗。患者接受治疗至少2年且无任何并发症。在此期间，他们最少接受3次、最多接受9次注射（平均6次）。
使用标准化心理方法在治疗前后测量社会心理数据。测量之间的时间跨度为1年8个月至4年6个月，平均为2年1个月。
平均而言，治疗前和治疗后均未检测到躯体疾病、无具有临床意义的焦虑状态或人格特质的病理表现。生活改变事件引起的平均压力负荷不明显。治疗前，11例患者中有5例存在情绪低落方面的情感障碍。这使得整个组的平均抑郁得分高于平均水平。治疗后未再发现。
抑郁被解释为一种心理反应。痉挛性嗓音症状与社会心理成因之间的关联无法得到证实。
