近端和远端结直肠癌之间Dukes分期的不同分布。
Different distribution of Dukes' stage between proximal and distal colorectal cancer.
作者信息
Ikeda Yoichi, Akagi Kazunari, Kinoshita Junko, Abe Toru, Miyazaki Mituhiro, Mori Masaki, Sugimachi Keizo
机构信息
Department of Surgery II, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
出版信息
Hepatogastroenterology. 2002 Nov-Dec;49(48):1535-7.
BACKGROUND/AIMS: As different features of colorectal cancer between proximal and distal sites are influenced mainly by proximal shift and diagnostic improvement, a comparison of proximal and distal cancer sites may provide clues as to appropriate strategy for colorectal cancer treatment.
METHODOLOGY
The clinicopathological data on 676 patients with colorectal cancer was compared regarding the proximal and distal sites.
RESULTS
In cases of cancer without metastasis (Dukes' A or B), the incidence of Dukes' A was higher in the distal than in the proximal site (11.2% vs. 24.3%), while the incidence of Dukes' B was lower in the distal than the proximal site. In cases of cancer with metastasis (Dukes' C or D), the incidence of Dukes' C and Dukes' D tumors was similar between proximal and distal sites.
CONCLUSIONS
A large number of Dukes' A cancer in distal site may be slow growing with low metastatic potential.
背景/目的：由于近端和远端结直肠癌的不同特征主要受近端转移和诊断改善的影响，比较近端和远端癌灶可能为结直肠癌的适当治疗策略提供线索。
方法
比较了676例结直肠癌患者近端和远端部位的临床病理数据。
结果
在无转移的癌症病例（Dukes' A或B期）中，Dukes' A期在远端的发生率高于近端（11.2%对24.3%），而Dukes' B期在远端的发生率低于近端。在有转移的癌症病例（Dukes' C或D期）中，近端和远端部位Dukes' C期和Dukes' D期肿瘤的发生率相似。
结论
远端部位大量的Dukes' A期癌症可能生长缓慢且转移潜能低。
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