Machiulskiene V, Richards A, Nyvad B, Baelum V
Clinic of Oral Pathology, Operative Dentistry and Endodontics, Faculty of Stomatology, Kaunas University of Medicine, Kaunas, Lithuania.
Caries Res. 2002 Sep-Oct;36(5):301-7. doi: 10.1159/000065955.
Previous studies have indicated that rinsing the mouth with a beaker of water after toothbrushing may compromise the caries reducing effect of fluoride toothpaste. A 3-year clinical trial of daily supervised brushing with fluoride toothpaste at school was used to test the effect of post-brushing rinsing with water on caries increment. A total of 407 children, mean age 11.8 years, attending three schools in Kaunas, Lithuania were enrolled following informed consent of the children and their parents. Caries was recorded at baseline and annually for 3 years. During the study, children in two schools (A and B) performed daily supervised brushing with a 1,500-ppm fluoride toothpaste. Children in school A rinsed their mouths thoroughly with a beaker of water after toothbrushing whereas children in school B were only permitted to spit out once after brushing. Furthermore, the children in these schools were supplied with toothpaste and toothbrushes for use at home and in school. A third school (C), without daily brushing and without supply of toothpaste, served as control. Compliance with the protocol was consistently better in school B. After 3 years 276 children were available for examination. Three-year DMFS increments, including non-cavitated lesions (mean, 95% CI), were: school A, 6.8 (5.3; 8.3); school B, 6.2 (4.6; 7.8), and school C, 12.4 (10.6; 14.1). Mean increments for schools A and B did not differ significantly but were both significantly lower than those of school C (p< 0.001). It is concluded that post-brushing rinsing with water, under the conditions of this study, does not significantly affect the caries reducing effect of a fluoride toothpaste.
先前的研究表明,刷牙后用一杯水漱口可能会削弱含氟牙膏的防龋效果。一项为期3年的在学校进行的、每日由专人监督使用含氟牙膏刷牙的临床试验,旨在测试刷牙后用水漱口对龋齿增加情况的影响。在立陶宛考纳斯的三所学校中,共有407名平均年龄为11.8岁的儿童在获得儿童及其家长的知情同意后被纳入研究。在基线时记录龋齿情况,并连续3年每年记录一次。在研究期间,两所学校(A校和B校)的儿童每日由专人监督使用1500 ppm的含氟牙膏刷牙。A校的儿童在刷牙后用一杯水彻底漱口,而B校的儿童在刷牙后只允许吐一次。此外,这些学校的儿童还获得了牙膏和牙刷,供在家和在学校使用。第三所学校(C校),既没有每日刷牙,也没有提供牙膏,作为对照。B校对方案的依从性一直更好。3年后,有276名儿童可供检查。三年的DMFS增加量,包括非龋损病变(均值,95%可信区间)为:A校,6.8(5.3;8.3);B校,6.2(4.6;7.8),C校,12.4(10.6;14.1)。A校和B校的平均增加量没有显著差异,但均显著低于C校(p<0.001)。得出的结论是,在本研究条件下,刷牙后用水漱口不会显著影响含氟牙膏的防龋效果。