Keller M K, Klausen B J, Twetman S
Community Dent Health. 2016 Mar;33(1):23-6.
In many Danish communities, school-based fluoride programs are offered to children with high caries risk in adjunct to tooth brushing. The purpose of this field trial was to compare the caries-preventive effectiveness of two different fluoride programs in 6-12 year olds.
Clinical controlled trial.
The 2-year study was conducted in Public Dental Clinics in a multicultural low-socioeconomic suburban area of Odense, Denmark with an elevated prevalence of caries compared to the city average.
1,018 children (aged 6-12 years) from 9 different schools were enrolled after informed consent and their class unit was randomly allocated to one of two fluoride programs.
One group received a semi-annual fluoride varnish applications (FV) and the other group continued with an existing program with fluoride mouth rinses once per week (FMR). All children received oral hygiene instructions and comprehensive dental care at the local Public Dental Clinics throughout the study period.
Increment of caries lesions in permanent teeth at both cavitated and initial caries levels.
The groups were balanced at baseline. After two years, 961 children (94.4%) were reexamined. The FV group showed a mean DMFS increment of 0.36 compared to 0.41 in the FMR group. The corresponding values for initial caries lesions were 0.83 and 0.91 respectively.
There were no statistically significant differences in caries development over two years among children participating in a school-based fluoride varnish or mouth rinse program.
在丹麦许多社区,除刷牙外,还为龋齿高风险儿童提供校内氟化物项目。本现场试验的目的是比较两种不同氟化物项目对6至12岁儿童的防龋效果。
临床对照试验。
这项为期两年的研究在丹麦欧登塞一个多元文化、社会经济地位较低的郊区的公共牙科诊所进行,该地区龋齿患病率高于城市平均水平。
来自9所不同学校的1018名儿童(6至12岁)在获得知情同意后入组,其班级单位被随机分配到两个氟化物项目之一。
一组每半年接受一次氟化物涂漆(FV),另一组继续实施现有的每周一次氟化物漱口水(FMR)项目。在整个研究期间,所有儿童在当地公共牙科诊所接受口腔卫生指导和全面的牙科护理。
恒牙龋损在龋洞形成和初始龋水平上的增加情况。
两组在基线时均衡。两年后,对961名儿童(94.4%)进行了复查。FV组的平均DMFS增量为0.36,而FMR组为0.41。初始龋损的相应值分别为0.83和0.91。
参与校内氟化物涂漆或漱口水项目的儿童在两年内龋齿发展方面没有统计学上的显著差异。