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[老年人的眼部感染]

[Ocular infections of the elderly].

作者信息

Labetoulle Marc, Lautier-Frau Marie, Frau Eric

机构信息

Service d'ophtalmologie Centre hospitalier universitaire de Bicêtre AP-HP, Le Kremlin-Bicêtre (94).

出版信息

Presse Med. 2002 Oct 5;31(32):1521-9.

Abstract

A CLINICAL ASPECT DEPENDING ON THE PHYSIOPATHOGENESIS

Ocular infections are a frequent motive for ophthalmological consultations in geriatric settings because of the mechanical factors related to age (modifications in palpebral dynamics and lacrymal function) and in local and general immune factors leading to the rapid and/or more severe development of infections. The mechanism of microbial contamination of the eye also determines the clinical damage: predominantly local (dirty hands, traumas) with involvement of the surface tissues (conjunctive and cornea) or general, hematogenic or neurogenic, frequently at the origin of more internal infections (iris, choroid, retina, optical nerve). CONJUNCTIVITIS AND KERATITIS: These provoke reddening of the eyes, tears and above all pain when the corneal epithelium is involved. Microbiological samples are useful in cases of severe, presumably infectious keratitis or conjunctivitis. Two emergency situations must be distinguished: any suspicion of herpes for which local corticosteroids are contraindicated and keratitis or conjunctivitis with the use of lenses, often due to Gram negative bacilli, amoeba or fungus, the treatment of which is intensive and the prognosis often severe. OPHTHALMOLOGICAL HERPES ZOSTER: The rapid diagnosis and introduction of efficient doses of antivirals reduces the initial pain, the ocular complications of herpes zoster and post-zoster pain. The latter, when it exists, requires specialized management. ACUTE UVEITIS: A context of intra-ocular inflammation in an elderly patient must always evoke a pseudo-uveitis syndrome, the principle cause of which is lymphoma. Conversely, an uveitis occurring in the days or weeks following ocular surgery, including cataract, must be considered as suggestive of a post-surgical infection and rapidly referred to a specialist. ACUTE DACRYOCYSTITIS: Is manifested by a hard and painful tumefaction below the internal angle of the eye. Following collection, it requires draining through an in incision in the skin, washing and packing of the sac, and systemic antibiotherapy. The preventive treatment of recurrences requires open dacryocystorhinostomy or via endonasal endoscopy.

摘要

基于病理生理学的临床方面

由于与年龄相关的机械因素(睑裂动力学和泪液功能改变)以及局部和全身免疫因素导致感染快速和/或更严重地发展,眼部感染是老年眼科会诊的常见原因。眼部微生物污染的机制也决定了临床损害:主要为局部感染(脏手、外伤),累及表面组织(结膜和角膜),或为全身感染、血源性或神经源性感染,常引发更内部的感染(虹膜、脉络膜、视网膜、视神经)。

结膜炎和角膜炎

当角膜上皮受累时,会引起眼睛发红、流泪,尤其是疼痛。微生物样本对严重的、可能为感染性的角膜炎或结膜炎病例有用。必须区分两种紧急情况:任何疑似疱疹的情况,局部使用皮质类固醇是禁忌的;以及使用隐形眼镜引起的角膜炎或结膜炎,通常由革兰氏阴性杆菌、阿米巴或真菌引起,其治疗需要强化治疗且预后往往严重。

眼科带状疱疹

快速诊断并给予有效剂量的抗病毒药物可减轻初始疼痛、带状疱疹的眼部并发症和带状疱疹后疼痛。后者若存在,则需要专业治疗。

急性葡萄膜炎

老年患者眼内炎症的情况必须始终考虑到假葡萄膜炎综合征,其主要病因是淋巴瘤。相反,在包括白内障在内的眼部手术后数天或数周内发生的葡萄膜炎,必须被视为提示术后感染,并应迅速转诊给专科医生。

急性泪囊炎

表现为内眼角下方坚硬且疼痛的肿胀。采集样本后,需要通过皮肤切口引流、冲洗和填塞泪囊,并进行全身抗生素治疗。预防复发需要进行开放性泪囊鼻腔吻合术或通过鼻内镜手术。

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