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眼部带状疱疹的眼部表现

Ocular manifestations in herpes zoster ophthalmicus.

作者信息

Puri L R, Shrestha G B, Shah D N, Chaudhary M, Thakur A

机构信息

Sagarmatha Choudhary Eye Hospital, Lahan, Nepal.

出版信息

Nepal J Ophthalmol. 2011 Jul-Dec;3(2):165-71. doi: 10.3126/nepjoph.v3i2.5271.

Abstract

BACKGROUND

Ocular complications of herpes zoster ophthalmicus (HZO) may lead to substantial visual disability, severe post-herpetic neuralgia and rarely fatal cerebral complications.

AIM

To identify the pattern of ocular manifestation in herpes zoster ophthalmicus.

MATERIALS AND METHODS

A cross-sectional descriptive study was under taken including the clinically diagnosed cases of HZO. All of them underwent a complete ophthalmological evaluation.

RESULTS

Sixty-eight cases of HZO were examined, of which 37 (54.4 %) were male and 31 (45.6%) female. The mean age was 48.7 ± 18.5 years. Most of the patients (64.7 %) were above the age of 40 years. 77.94 % of the patients had some form of ocular involvement. Pain (77.9 %) was the commonest ocular complaint. In young patients less than 35 years, HIV was the most common risk factor (19.3 %).Visual status was good in the majority (73.5 %) of patients at presentation. Lid and adnexal findings (45.8 %) were most common ocular involvement followed by conjunctivitis (41.1 %). Corneal complication was seen in 38.2 % of cases, uveitis in 19.1 % and post-herpetic neuralgia (PHN) and secondary glaucoma each in 5.8 %.

CONCLUSION

Eyelid and ocular adnexal involvement is most commonly found in patients with herpes zoster ophthalmicus followed by corneal complication and uveitis. There needs to be awareness of ocular involvement, which can be sight threatening, among the HZO patients and other medical departments and an increased emphasis on regular ophthalmic examination.

摘要

背景

眼部带状疱疹(HZO)的眼部并发症可能导致严重的视力残疾、严重的疱疹后神经痛,以及罕见的致命性脑部并发症。

目的

确定眼部带状疱疹的眼部表现模式。

材料与方法

进行了一项横断面描述性研究,纳入临床诊断为HZO的病例。所有患者均接受了全面的眼科评估。

结果

检查了68例HZO患者,其中男性37例(54.4%),女性31例(45.6%)。平均年龄为48.7±18.5岁。大多数患者(64.7%)年龄在40岁以上。77.94%的患者有某种形式的眼部受累。疼痛(77.9%)是最常见的眼部症状。在35岁以下的年轻患者中,HIV是最常见的危险因素(19.3%)。大多数患者(73.5%)就诊时视力状况良好。眼睑及附属器病变(45.8%)是最常见的眼部受累情况,其次是结膜炎(41.1%)。38.2%的病例出现角膜并发症,19.1%出现葡萄膜炎,疱疹后神经痛(PHN)和继发性青光眼各占5.8%。

结论

眼部带状疱疹患者最常出现眼睑及眼部附属器受累,其次是角膜并发症和葡萄膜炎。HZO患者以及其他医学科室需要意识到眼部受累可能威胁视力,并应更加重视定期眼科检查。

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