Xu Hui-Xiong, Zhang Qing-Ping, Lu Ming-De, Xiao Xian-Tao
Department of Medical Ultrasonics, The First Affiliated Hospital, Sun Yat-Sen University, 58 Zhongshan II Road, Guangzhou 510080, People's Republic of China.
J Clin Ultrasound. 2002 Nov-Dec;30(9):515-25. doi: 10.1002/jcu.10109.
We assessed the differences between 2-dimensional (2D) and 3-dimensional (3D) sonography (US) in evaluating fetal malformations.
Both 2D US and 3D US were used to examine pregnant women whose fetuses had malformations. The diagnostic information provided by the modalities was evaluated and compared.
A total of 62 malformations were confirmed by postnatal or postmortem follow-up in 41 fetuses of 40 pregnant women. 2D US made a definite and correct diagnosis of 49 malformations (79%), whereas 3D US definitely diagnosed 58 malformations (94%) (p < 0.01). 3D US definitely diagnosed all the abnormalities in 38 fetuses (93%), whereas 2D US did so in only 32 fetuses (78%) (p < 0.05). In 35 (60%) of the 58 malformations revealed by both 3D US and 2D US, the former provided more diagnostic information than the latter. 3D US was particularly superior to 2D US in evaluating fetal malformations of the cranium and face, spine and extremities, and body surface.
In comparison with 2D US, 3D US improves the diagnostic capability by offering more diagnostic information in evaluating fetal malformations, particularly in displaying fetal malformations of the cranium and face, spine and extremities, and body surface. 3D US is a valuable adjunct to 2D US in prenatal diagnosis.
我们评估了二维（2D）和三维（3D）超声检查（US）在评估胎儿畸形方面的差异。
使用二维超声和三维超声对胎儿有畸形的孕妇进行检查。对这两种检查方式提供的诊断信息进行评估和比较。
40名孕妇的41例胎儿经产后或死后随访共确诊62处畸形。二维超声明确正确诊断出49处畸形（79%），而三维超声明确诊断出58处畸形（94%）（p<0.01）。三维超声明确诊断出38例胎儿的所有异常（93%），而二维超声仅诊断出32例胎儿的所有异常（78%）（p<0.05）。在三维超声和二维超声均显示的58处畸形中的35处（60%），前者提供的诊断信息比后者更多。三维超声在评估胎儿颅脑面部、脊柱四肢及体表畸形方面尤其优于二维超声。
与二维超声相比，三维超声在评估胎儿畸形时能提供更多诊断信息，从而提高诊断能力，尤其是在显示胎儿颅脑面部、脊柱四肢及体表畸形方面。三维超声是二维超声产前诊断的重要辅助手段。
