Trotter James F.
Division of Gastroenterology/Hepatology, University of Colorado Health Sciences Center, 4200 East 9th Avenue, B-154, Denver, CO 80262, USA.
Curr Treat Options Gastroenterol. 2002 Dec;5(6):491-501. doi: 10.1007/s11938-002-0037-7.
Adult-to-adult right hepatic lobe living donor liver transplantation (LDLT) has rapidly emerged as an accepted treatment option for selected patients with end-stage liver disease. The two most important determinants in patient outcome are the careful selection of recipients, and the technical skill and experience of the surgical team. The most appropriate candidates for LDLT are patients who require an expedited transplant. Also, the candidate must not have significant comorbid conditions that could jeopardize the success of the procedure. The initial outcomes of LDLT recipients are similar to recipients with a cadaveric liver. However, direct comparison may not be possible, because LDLT recipients are currently selected for favorable outcomes. Most LDLT donors are able to undergo right-sided hepatectomy without significant morbidity. However, the risk of death associated with donation is estimated to be 1/300; approximately 20% have a measurable complication.
成人对成人右肝叶活体肝移植（LDLT）已迅速成为一种被认可的治疗终末期肝病特定患者的选择。影响患者预后的两个最重要决定因素是受者的精心挑选以及手术团队的技术水平和经验。LDLT最适合的候选者是那些需要快速进行移植的患者。此外，候选者不得有可能危及手术成功的严重合并症。LDLT受者的初始预后与尸体肝受者相似。然而，由于目前选择LDLT受者是为了获得良好预后，所以可能无法进行直接比较。大多数LDLT供者能够接受右侧肝切除术且无明显并发症。然而，与捐献相关的死亡风险估计为1/300；约20%有可测量的并发症。
