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[韧带样瘤]

[Desmoids tumors].

作者信息

Dequanter D, Gebhart M

机构信息

Département de Chirurgie, Institut Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles - Bruxelles, France.

出版信息

J Chir (Paris). 2002 Sep;139(4):236-9.

Abstract

Desmoid tumor can be defined as a pseudoencapsulated infiltrative growth of well-differentiated collagenous fibroblasts and fibrocytes arising either in fascia or musculoaponeurotic structures. The etiology of desmoid tumors is poorly defined. The most commonly implicated etiologic factors are trauma, hormonal disturbances, and genetic or hereditary factors. Desmoid tumors of the anterior abdominal wall are much less common than extra-abdominal desmoids; they may occur at any age but are most common in the third and fourth decades. Although both sexes may be affected, abdominal desmoids predominate in females, particularly in females of childbearing age. Extra-abdominal desmoids, which most commonly occur on the back, chest wall, head and neck, or lower extremity, have a male predominance. Most patients complain of a painless mass of several months or years' duration. The primary consideration in surgical treatment of desmoid tumors should be the prevention of local recurrence. In most instances, this can be achieved by wide local excision or muscle group resection. There is no clear evidence that irradiation or chemotherapy are effective in controlling desmoid tumors.

摘要

硬纤维瘤可定义为起源于筋膜或肌-腱膜结构的、由分化良好的胶原纤维母细胞和纤维细胞构成的假包膜浸润性生长物。硬纤维瘤的病因尚不明确。最常涉及的病因因素是创伤、激素紊乱以及遗传或遗传因素。前腹壁硬纤维瘤比腹外硬纤维瘤少见得多;可发生于任何年龄,但最常见于第三和第四个十年。虽然两性均可受累,但腹部硬纤维瘤在女性中占主导,尤其是育龄女性。腹外硬纤维瘤最常见于背部、胸壁、头颈部或下肢,以男性为主。大多数患者主诉有持续数月或数年的无痛性肿块。硬纤维瘤手术治疗的首要考虑应是预防局部复发。在大多数情况下,这可通过广泛局部切除或肌群切除来实现。没有明确证据表明放疗或化疗对控制硬纤维瘤有效。

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