Sperling Brita L, Cockcroft Donald W, Chibbar Rajni
Department of Pathology, University of Saskatchewan, Royal University Hospital, Saskatoon, Canada.
Can Respir J. 2002 Sep-Oct;9(5):347-50. doi: 10.1155/2002/439459.
The present report describes the first reported case of microscopic pulmonary tumour embolism (MPTE) from thymic carcinoma. The carcinoma was discovered during an autopsy in a 55-year-old man who had undergone surgery for a pilonidal sinus two weeks before presentation. Pulmonary thromboembolism was suspected. This case was unusual because MPTE has never before been associated with thymic carcinoma, MPTE was the first clinical indication of an occult malignancy, and the clinical presentation was that of sudden onset of dyspnea associated with acute cor pulmonale. The cause of death was determined to be hypoxia secondary to extrinsic compression of the right pulmonary artery and extensive tumour emboli in the small arteries, arterioles and venules of the pulmonary parenchyma. A review of the clinical presentation and diagnosis of MPTE is included.
本报告描述了首例有报道的来自胸腺癌的微小肺肿瘤栓塞（MPTE）病例。该肿瘤是在一名55岁男性尸检时发现的，该男性在出现症状前两周因藏毛窦接受了手术。怀疑有肺血栓栓塞。此病例不同寻常，因为此前MPTE从未与胸腺癌相关联，MPTE是隐匿性恶性肿瘤的首个临床指征，且临床表现为突发呼吸困难并伴有急性肺心病。死因确定为右肺动脉外部受压及肺实质小动脉、小动脉和小静脉中广泛的肿瘤栓子继发的缺氧。本文还包括对MPTE临床表现和诊断的综述。
