Umbert Millet P, Winkelmann R K
Med Cutan Ibero Lat Am. 1975;3(3):241-6.
27 patients affected of lymphoproliferative processes, 9 with different non-granulomatous dermatosis and 40 controls are studied by the authors. The technique David & David is used to determine the inhibition of the migration of macrophages in capillary tubes, adding to the culture medium the serum of the patient. They find MIF-like activity in the serum of three patients affected by the sezary syndrome. All sutdied cases of cutaneous lymphoma, non granulomatous dermatosis and healthy controls are negative.
作者对27例患有淋巴增生性疾病的患者、9例患有不同非肉芽肿性皮肤病的患者以及40名对照者进行了研究。采用大卫氏技术,通过向培养基中添加患者血清来测定毛细管中巨噬细胞迁移的抑制情况。他们在3例患有塞扎里综合征的患者血清中发现了类巨噬细胞移动抑制因子活性。所有研究的皮肤淋巴瘤、非肉芽肿性皮肤病病例及健康对照均为阴性。