Huang Hefeng, Zhu Yimin, Zhou Fuzhen, Xu Jian, Ye Yinghui
Department of Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Zhonghua Fu Chan Ke Za Zhi. 2002 Sep;37(9):533-5.
To report the outcomes of transvaginal ultrasound-guided multifetal pregnancy reduction (MFPR) in early high-order multiple gestation.
Fifty-five cases of high-order multiple pregnancy including 1 septuplet, 7 quintuplets, 16 quadruplets and 31 triplets resulted from either superovulation/intrauterine insemination or in vitro fertilization-embryo transfer, were treated by transvaginal ultrasound guided MFPR at 49 - 79 days of gestational age. Their outcomes and complications were reported.
Multifetal reduction were successfully done in 53 cases (96%). Miscarriage occurred in 8 patients (15%). Twenty-one cases (47%) were premature delivery and 24 patients underwent term delivery resulting in 87 infants. Five preterm infants died of neonatal respiratory distress syndrome. Among them none has malformation. Of the 82 live infants, 1 had hexadactyly and another arterial septum defect occurred. No organ injury, massive hemorrhage and infection occurred after MFPR.
MFPR during early pregnancy is a safe, effective, simple operation for the purpose of reducing perinatal and maternal complication.
报告经阴道超声引导下对早期高阶多胎妊娠进行多胎减胎术（MFPR）的结果。
55例高阶多胎妊娠病例，包括1例七胞胎、7例五胞胎、16例四胞胎和31例三胞胎，这些病例由超排卵/宫内人工授精或体外受精 - 胚胎移植所致，在孕49 - 79天接受经阴道超声引导下的MFPR治疗。报告其结果及并发症。
53例（96%）成功进行了多胎减胎。8例（15%）发生流产。21例（47%）早产，24例足月分娩，共娩出87名婴儿。5名早产婴儿死于新生儿呼吸窘迫综合征。其中无畸形儿。在82名存活婴儿中，1例有六指畸形，另1例发生房间隔缺损。MFPR术后未发生器官损伤、大出血及感染。
孕早期进行MFPR是一种安全、有效、简便的手术，可减少围产期及母体并发症。
