Qi Qiping, Yang Yanwei, Yao Xiaoyuan, Ding Liang, Wang Wen, Liu Yunyuan, Chen Yuan, Yang Zhiping, Sun Yudong, Yuan Baoshan, Yu Chuanlong, Han Liangfeng, Liu Xue, Hu Xiaohong, Liu Yaping, Du Zhengdong, Qu Liping, Sun Fang
Department of Biological Monitoring, Institute for Environment Hygiene and Health Related Product Sefety, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2002 Jun;23(3):162-6.
The purpose of this study was to investigate the blood lead level of 3 - 5 year old children living in the cities in China and to provide scientific data for making policy on environmental lead pollution for children health protection.
Six thousand five hundred and two vein blood samples from 3 - 5 year old children in nineteen cities of nine provinces were sampled. Inductively coupled plasma-mass spectrometry (ICP-MS) were employed to determine lead level in whole blood after microwave digestion for sample preparation and questionnaire survey was also performed. Data were analyzed with multiple regression on factors which affecting blood lead levels.
Results showed that mean blood lead level was 88.3 micro g/L for 3 - 5 year old children living in the cities in China and mean blood lead level of boys (91.1 micro g/L) was higher than that of girls (87.3 micro g/L). Twenty-nine point nine one per cent of the children's blood lead level exceeded 100 micro g/L. The research finding showed: (1) higher blood lead levels had negative effects on children's physical growth, language ability etc. (2) behavior of parents had certain effects on children's blood lead levels. (3) blood lead levels of children were affected by unhealthy habits.
Problem of childhood lead poisoning in China has become more serious. During the past ten years, blood lead levels of children has been increased in China while decreasing in developed countries. Blood lead levels of children in China are higher than that of developed countries, which called for special concern by government and society.
本研究旨在调查中国城市3至5岁儿童的血铅水平,为制定保护儿童健康的环境铅污染政策提供科学依据。
采集了来自9个省份19个城市的6502名3至5岁儿童的静脉血样本。采用电感耦合等离子体质谱法(ICP-MS),经微波消解制备样本后测定全血铅含量,并进行问卷调查。对影响血铅水平的因素进行多元回归分析。
结果显示,中国城市3至5岁儿童的平均血铅水平为88.3μg/L,男孩的平均血铅水平(91.1μg/L)高于女孩(87.3μg/L)。29.91%的儿童血铅水平超过100μg/L。研究结果表明:(1)血铅水平升高对儿童身体发育、语言能力等有负面影响。(2)家长行为对儿童血铅水平有一定影响。(3)儿童血铅水平受不良习惯影响。
中国儿童铅中毒问题日益严重。在过去十年中,中国儿童血铅水平呈上升趋势,而发达国家则呈下降趋势。中国儿童血铅水平高于发达国家,这需要政府和社会特别关注。