Li Ying, Wu Siqi, Xiang Yun, Liang Xiaohui
Wuhan Children's Hospital, Wuhan, China.
School of Public Health, Wuhan University, Wuhan, China.
PLoS One. 2014 Apr 16;9(4):e95284. doi: 10.1371/journal.pone.0095284. eCollection 2014.
Blood lead levels (BLLs) and possible influencing factors in children in Wuhan China were investigated in order to understand current lead pollution exposure and provide a scientific basis for prevention and policy making.
BLL data were collected from 15,536 out-patients in Wuhan Children Hospital in 2012 full year. All of them were under 18 years of age (Mean ± SD: 4.32 ± 3.2, 64.4% boys). The BLLs were measured by an atomic absorption spectrometry (BH2100).
The geometric mean of BLLs for all the subjects was 44.75 µg/L (95%CI: 44.46 µg/L - 45.05 µg/L), much lower than that reported in previous studies. The prevalence of the elevated BLLs (≥ 100 µg/L) in the children tested was 2% in 2012 and the prevalence of BLLs (≥ 50 µg/L) was 44%. Age and sex could be possible influencing factors for BLLs in the children (p<0.001). In addition, the BLLs in different seasons were different (p<0.001).
These results demonstrate that BLLs have significantly decreased in children in Wuhan during recent years. However, we should continuously pay attention to lead pollution and emphasize that prevention is much more important than treatment for controlling children's BLLs.
调查中国武汉儿童的血铅水平（BLLs）及其可能的影响因素，以了解当前铅污染暴露情况，并为预防和政策制定提供科学依据。
收集2012年全年武汉儿童医院15536名门诊患儿的血铅水平数据。所有患儿年龄均在18岁以下（均值±标准差：4.32±3.2，男孩占64.4%）。血铅水平采用原子吸收光谱法（BH2100）测定。
所有受试者血铅水平的几何均值为44.75μg/L（95%置信区间：44.46μg/L - 45.05μg/L），远低于先前研究报道的水平。2012年检测儿童中血铅水平升高（≥100μg/L）的患病率为2%，血铅水平（≥50μg/L）的患病率为44%。年龄和性别可能是儿童血铅水平的影响因素（p<0.001）。此外，不同季节的血铅水平有所不同（p<0.001）。
这些结果表明，近年来武汉儿童的血铅水平显著下降。然而，我们应持续关注铅污染，并强调对于控制儿童血铅水平而言，预防远比治疗更为重要。
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