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一些可作为治疗靶点的寄生虫的生化和代谢特性。

Biochemical and metabolic peculiarities of some parasites availing as targets for therapy.

作者信息

Frayha G J, Gobert J G, Savel J

机构信息

Faculty of Pharmaceutical and Biological Sciences, University of René Descartes, Paris, France.

出版信息

J Med Liban. 2001 Jul-Aug;49(4):210-27.

Abstract

Biochemical and metabolic peculiarities of some parasites involved in their interactions with their hosts are reviewed according to (1) carbohydrate metabolism comprising glycolysis, Pasteur effect, CO2 fixation and electron transport system; (2) amino acid and protein metabolism ; (3) purine and pyrimidine nucleotides metabolism. These peculiarities are becoming targets for treatment without affecting the host.

摘要

根据以下方面综述了一些寄生虫在与宿主相互作用中所涉及的生化和代谢特性

(1)碳水化合物代谢,包括糖酵解、巴斯德效应、二氧化碳固定和电子传递系统;(2)氨基酸和蛋白质代谢;(3)嘌呤和嘧啶核苷酸代谢。这些特性正成为在不影响宿主的情况下进行治疗的靶点。

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