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采用 I-123-β-甲基-碘苯基十五烷酸和 I-123-间碘苄胍心肌闪烁显像对应激性心肌病进行六个月随访

Six-month follow-up of takotsubo cardiomyopathy with I-123-beta-metyl-iodophenyl pentadecanoic acid and I-123-meta-iodobenzyl-guanidine myocardial scintigraphy.

作者信息

Moriya Manabu, Mori Hideki, Suzuki Nobuaki, Hazama Minoru, Yano Katsusuke

机构信息

Department of Cardiology, The Japanese Red Cross Nagasaki Atomic Bomb Hospital.

出版信息

Intern Med. 2002 Oct;41(10):829-33. doi: 10.2169/internalmedicine.41.829.

DOI:10.2169/internalmedicine.41.829
PMID:12413004
Abstract

A 69-year-old man with a history of transient chest pain was diagnosed takotsubo cardiomyopathy. In I-123-beta-metyl-iodophenyl pentadecanoic acid myocardial scintigraphy, decreased uptake of apex was seen in the acute phase, and it recovered in 3 months. In I-123-meta-iodobenzyl-guanidine myocardial scintigraphy, decreased uptake of apex persisted for 6 months, and there was a discrepancy between apical and total washout rate in the acute phase and after 3 months, which disappeared after 6 months. We speculate that the discrepancy of sympathetic innervation between the apical and basal region is the cause of the characteristic left ventricular apical akinesia of takotsubo cardiomyopathy.

摘要

一名有短暂胸痛病史的69岁男性被诊断为应激性心肌病。在I-123-β-甲基-碘代苯基十五烷酸心肌闪烁显像中,急性期可见心尖部摄取减少,3个月后恢复。在I-123-间碘苄胍心肌闪烁显像中,心尖部摄取减少持续6个月,急性期和3个月后心尖部与总洗脱率之间存在差异,6个月后消失。我们推测,应激性心肌病特征性左心室心尖部运动障碍的原因是心尖部和基底部区域交感神经支配的差异。

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