Passler Christian, Avanessian Raymond, Kaczirek Klaus, Prager Gerhard, Scheuba Christian, Niederle Bruno
Division of General Surgery-Endocrine Surgery, Department of Surgery, University Hospital, Vienna, Austria.
Arch Surg. 2002 Nov;137(11):1243-8. doi: 10.1001/archsurg.137.11.1243.
Although age itself is no contraindication for major surgical procedures, few patients 75 years and older undergo thyroid surgery.
Thyroid surgery in the geriatric patient can be performed with low morbidity and mortality.
Retrospective analysis of prospectively documented data.
University hospital referral center.
We included 738 patients undergoing thyroid surgery within 5 years, of whom 55 (7.5%) were 75 years or older (group 1) (mean +/- SD age, 79.9 +/- 4.1 years).
Indication for surgery, surgical strategy, morbidity, and mortality were analyzed and compared with those in younger patients (<75 years; group 2).
Malignancy was suspected or verified in 29 patients (52.7%) in group 1; 21 (38.2%) had mechanical symptoms due to large bilateral nodular goiters; and 5 (9.1%) presented with benign nodular goiter. The main indication in group 2 (n = 683) was benign nodular goiter in 455 (66.6%); 142 patients (20.8%) presented with suspected malignancy and 21 (3.1%) with mechanical symptoms (P<.001). Most patients underwent total thyroidectomy, hemithyroidectomy, or near-total thyroidectomy (n = 50 [90.9%; group 1] vs n = 597 [87.4%; group 2]; P =.53). Frequency of malignancy was higher in group 1 ([n = 20 [36.4%] vs n = 179 [26.2%]; P =.17). Morbidity of thyroid surgery was comparable in both groups. One (2.3%) of 44 patients in group 1 had permanent hypoparathyroidism, compared with 10 (2.0%) of 502 in group 2 (P =.61); permanent recurrent laryngeal nerve paralysis occurred in 1 (1.05%) of 95 nerves at risk in group 1 compared with 3 (0.26%) of 1172 nerves at risk in group 2 (P =.22). There was no perioperative mortality in either group.
Thyroid surgery in patients 75 years or older can be performed with low morbidity. The guarantees for success include an individual risk-and-benefit analysis and careful preoperative preparation.
尽管年龄本身并非重大外科手术的禁忌证,但75岁及以上的患者很少接受甲状腺手术。
老年患者的甲状腺手术可以在低发病率和低死亡率的情况下进行。
对前瞻性记录的数据进行回顾性分析。
大学医院转诊中心。
我们纳入了5年内接受甲状腺手术的738例患者,其中55例(7.5%)年龄在75岁及以上(第1组)(平均±标准差年龄,79.9±4.1岁)。
分析手术指征、手术策略、发病率和死亡率,并与年轻患者(<75岁;第2组)进行比较。
第1组29例(52.7%)患者怀疑或确诊为恶性肿瘤;21例(38.2%)因双侧巨大结节性甲状腺肿出现机械性症状;5例(9.1%)为良性结节性甲状腺肿。第2组(n = 683)的主要指征是455例(66.6%)良性结节性甲状腺肿;142例(20.8%)怀疑有恶性肿瘤,21例(3.1%)有机械性症状(P<0.001)。大多数患者接受了全甲状腺切除术、半甲状腺切除术或近全甲状腺切除术(第1组n = 50例[90.9%] vs第2组n = 597例[87.4%];P = 0.53)。第1组的恶性肿瘤发生率更高([n = 20例(36.4%) vs n = 179例(26.2%);P = 0.17])。两组甲状腺手术的发病率相当。第1组44例患者中有1例(2.3%)发生永久性甲状旁腺功能减退,第2组502例中有10例(2.0%)(P = 0.61);第1组95条有风险的喉返神经中有1条(1.05%)发生永久性喉返神经麻痹,第2组1172条有风险的喉返神经中有3条(0.26%)(P = 0.22)。两组均无围手术期死亡。
75岁及以上患者的甲状腺手术可以在低发病率的情况下进行。成功的保证包括个体风险效益分析和仔细的术前准备。