van Holten Jacqueline, Kunz Patrik, Mulder Paul G H, Pattynama Peter M T, Lamb Hildo J, van Dijk Lukas C
Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Dr Molewaterplein 40, 3015GD Rotterdam, The Netherlands.
MAGMA. 2002 Nov;15(1-3):52-7. doi: 10.1007/BF02693844.
Peak systolic velocity (PSV) measurements of blood flow inside vascular stents allow reliable detection of in-stent re-stenosis. The purpose of this in vitro study was to evaluate the feasibility of obtaining PSV measurements inside vascular stents made of Stainless Steel and Nitinol, using a velocity encoded MR technique.
MATERIALS/METHODS: In a flow phantom, stents of Stainless Steel and Nitinol were studied. The phantom was integrated into a closed-tubing circuit driven by a MR dedicated pulsatile flow pump. MR imaging was performed on a 1.5 T system. The PSV in the tube without stent was used as the gold standard to determine the accuracy and the variability (paired t-test and Pittman's test) of the PSV measurements inside the stents.
PSV values inside the stents showed percentual difference in mean of -15 to 21% (P < 0.05) at a pump setting of 10 and 20 ml/s.
PSV measurements can be accurately obtained inside stents made of Stainless Steel and Nitinol. MR-velocity measurements may be used in patients to non-invasively evaluate stent patency and in-stent re-stenosis.
通过测量血管支架内血流的收缩期峰值速度（PSV），能够可靠地检测支架内再狭窄情况。本体外研究的目的是评估使用速度编码磁共振技术获取不锈钢和镍钛诺制成的血管支架内PSV测量值的可行性。
材料/方法：在一个流动模型中研究了不锈钢和镍钛诺支架。该模型被整合到一个由磁共振专用脉动流泵驱动的封闭管道回路中。在一台1.5T系统上进行磁共振成像。将无支架时管道内的PSV用作金标准，以确定支架内PSV测量值的准确性和变异性（配对t检验和皮特曼检验）。
在泵流速设置为10和20ml/s时，支架内的PSV值平均百分比差异为-15%至21%（P<0.05）。
可以准确获取不锈钢和镍钛诺制成的支架内的PSV测量值。磁共振速度测量可用于患者，以无创评估支架通畅性和支架内再狭窄情况。
